Letting the client pace around the hallway from others.
Briefing :They can burn off their energy without irritating other clients if you let them pace. Their current mental state prevents them from focusing on anything else.
What is pace ?Program of All-Inclusive Care for the Older (PACE) is a sort of HCBS that helps some elderly people with their basic requirements, the majority of whom are qualified for both Medicare and Medicaid benefits, by offering medical services.
How does it work?When necessary, PACE offers coverage for prescription medications, doctor visits, transportation, home care, checkups, hospital visits, and even stays in nursing homes. Your ability to pay won't ever prevent you from receiving the care you require with PACE.
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abnormal study with electrophysiologic evidence of bilateral mild saensorimotor demyelinating median neuropathy at the wrist
Neuropathies involving demyelination can be chronic, subacute, or abrupt. They exhibit delayed nerve conduction velocities, diminished reflexes, weakness, and discriminative sensory loss.
Among the etiologies are autoimmune mechanisms, hereditary factors, poisons, and infections. Both acute and chronic demyelinating polyradiculoneuropathies are characterized by cerebral spinal fluid investigations that show an increased protein without a cellular response.
More accurate diagnoses are now achievable thanks to developments in genetics and immunology. Immune modifying treatments are used to treat autoimmune neuropathies. Steroids, intravenous immunoglobulins, plasma exchange, and immunosuppressive drugs may all be used in this situation. The inherited neuropathies are still without effective treatments.
Less frequently occurring now are the infectious causes of demyelinating neuropathies, such as leprosy and diphtheria. The diagnosis of demyelinating neuropathies still heavily weighs toxicity exposure.
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a covered entity is someone or an organization that a. provides direct patient care. b. transmits information about patient care or financial aspects of patient care. c. has access to medical records. d. is only involved in financial aspects of patient care. 2. the hipaa privacy rule recognizes and requires that
Option (b) is correct answer because covered entity is someone that transmits information about patient care or financial aspects of patient care in electronic form in connection with HIPPA transaction.
Rest options are incorrect.
Ans2:- Option (c) is correct answer because HIPPA privacy rule recognizes and requires a patient's "protected" health information is confidential, and must be protected.
Ans:3- Option (a) is correct answer that protected health information includes any information that concerns the health status of an individual. It may include health information and other information on treatment or care that is transmitted or maintained in any form or medium(electronic, paper, oral.
Ans:4- Option (c) is correct answer that Protected health information is information that is in written, electronic, or verbal form. Rest options are incorrect because they are not complete.
All the 4 question answers are explanation of each other.
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the diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the american association for the study of liver diseases
Fat deposits in your liver may be visible through imaging tests. Certain imaging examinations, such as specialized ultrasound and MRI scans, can aid in the disease's diagnosis and reveal liver scar tissue.
What is nonalcoholic fatty liver disease?An instance of stenosis that is brought on by causes other than excessive alcohol consumption is non-alcoholic fatty liver disease.
Although the specific reason is not fully understood, other metabolic problems such excessive cholesterol, obesity, and diabetes frequently co-occur.
However, a liver biopsy is required to confirm that fatty liver disease is the only factor in liver damage.
Therefore, MRI scans are used to diagnosis and management of nonalcoholic fatty liver disease,
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charlotte liked to have a suntan all of the time, so she never wore sunscreen at the beach or in the tanning salon. during a visit to her doctor, she was told that she has the most common form of skin cancer. she will be all right, but she should avoid prolonged exposure to uv radiation in the future. which skin cancer does she have?
Based on the description above, the skin cancer that charlotte have is known to be basal cell carcinoma.
What is basal cell carcinoma?The term Basal cell carcinoma is known to be a kind or type of skin cancer that is known to be grown or seen on areas of skin that is said to be exposed to the sun, an example is the face.
It often forms bumps on brown and Black skin. Therefore, Based on the description above, the skin cancer that charlotte have is known to be basal cell carcinoma.
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As perceived by an examiner, which is an objective finding such as a fever, a rash, or the whisper heard over the chest in pleural effusion?
The accumulation of extra fluid between the layers of the pleura outside the lungs is known as a pleural effusion, also known as "water on the lungs." Often a sharp pain is felt during a deep breath, which is a common objective finding.
The pleura, which are tiny membranes that line the chest cavity and the lungs, help to lubricate and assist breathing. The pleura typically contains a tiny amount of fluid.
The underlying cause of the pleural effusion, whether breathing is impacted, and whether it is treatable efficiently all determine how serious the illness is.
Treatment-effective pleural effusion causes include viral infections, pneumonia, and heart failure. Therapy of related mechanical issues and treatment of the underlying cause of the pleural effusion are two things that need to be taken into account.
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a nurse at an ophthalmology clinic is providing teaching to a client who has open-angle glaucoma and a new treatment regimen of timolol and pilocarpine eye drops. which of the following instructions should the nurse provide?
The nurse should instruct that (C) the medication should be applied on a regular schedule for the rest of the client's life.
A subtype of glaucomas known as primary open angle glaucoma (POAG) is characterized by an open, seemingly normal anterior chamber angle and elevated intraocular pressure (IOP), with no additional underlying illness. Secondary glaucoma is a condition where the elevated IOP has a known underlying etiology.
The goal of open angle glaucoma medications is to increase sufficient outflow, reduce its generation, or both. For the rest of their lives, the patient must keep using the eyedrops to keep their intraocular pressure at a manageable level.
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Question correction:
A nurse at an Ophthalmic G clinic is providing teaching to a client who has an open angle glaucoma and a new prescription for timolol eye drops. Which of the following instruction should the nurse provide?
A) the medication is to be applied when the client is expressing our pain
B) the medication will be used into the client in ocular pressure return to normal
C) the medication should be applied on a regular schedule for the rest of the clients life
D) the medication is to be used for approximately 10 days following a gradual tapering off
a nurse is providing teaching about the gastrostomy tube feedings to the parents of a school age child. whichof the following instructions should the nurse take?a. administer the feeding over 30 min.b. place the child in as supine position after the feeding.c. charge the feeding bag and tubing every 3 days.d. warm the formula in the microwave prior to administration.
The instructions should the nurse take is to Administer the feeding over 30 min
What is gastrostomy tube ?A gastrostomy tube, often known as a G-tube, is an implanted medical tool that provides direct access to your child's stomach for additional feeding, hydration, or medicine. G-tubes are utilised for a number of medical issues, however feedings to improve your child's nutrition are the most popular application.
For a variety of health issues, including congenital (existing at birth) issues with the mouth, oesophagus, stomach, or intestines, children require G-tubes. abnormalities of swallowing and sucking (due to premature birth, injury, a developmental delay, or another condition)Learn more about Gastronomy here:
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a client is being screened for a parasitic infection and the physician orders stool specimens. when explaining to the client about collecting the specimens, the nurse would inform the client that the specimens will be collected daily for:
Answer:
Daily to make sure that the patients health is increasing and that they are remaining healthy.
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which of these assessment findings would help convince the emt that a patient with abdominal pain and vaginal bleeding is experiencing a spontaneous abortion (miscarriage)?
Last menstrual period six weeks ago will help convince the emt that the patient is experiencing a spontaneous abortion.
Unintentional embryonic or fetal death or passing before 20 weeks of gestation is referred to as spontaneous abortion. A woman with a proven viable intrauterine pregnancy may have threatened abortion if she experiences vaginal bleeding without cervical dilatation during this period. Ultrasonography and clinical criteria are used in the diagnosis.
When a spontaneous abortion threatens or has already happened, the typical course of treatment is expectant observation, followed by observation or uterine evacuation. Cramping pelvic discomfort, bleeding, and finally tissue evacuation are signs of spontaneous abortion.
When the membranes tear, a late spontaneous abortion may start with a burst of fluid. Rarely is hemorrhage massive. Abortion is unavoidable when the cervix is dilated.
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magee la, abalos e, von dadelszen p, sibai b, easterling t, walkinshaw s. how to manage hypertension in pregnancy effectively. br j clin pharmacol. sep 2011;72(3):394-401.
To manage hypertension in pregnancy effectively given an antihypertensive medication as soon as possible, but at least within one hour.
Hypertension in pregnancy :The following dangers are associated with high blood pressure during pregnancy: a reduction in blood flow to the placenta. The fetus may obtain less oxygen and nutrients if the placenta doesn't get enough blood. Low birth weight, intrauterine growth restriction, and premature birth can result from this.
What causes hypertension in pregnancy?High blood pressure during pregnancy may result from unhealthy lifestyle choices. Major risk factors for high blood pressure include being overweight or obese and not exercising regularly.
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I understand question you are looking for :
how to manage hypertension in pregnancy effectively.
What is the relationship between piriformis syndrome and sciatica?
a client is hospitalized 3 days prior to a total hip arthroplasty and reports a high level of pain with ambulation. the client has been taking warfarin at home, which is now discontinued. to prevent the formation of blood clots, which action should the nurse take?
To prevent the formation of blood clots, the nurse should suggest administering the prescribed enoxaparin (Lovenox) to the client.
Hip replacement is kind of a surgical technique in which a person's prosthetic implant, or hip prosthesis, is used to replace the hip joint. Hip replacement surgery can also be done as a full or partial replacement.
What is a hip arthroplasty?Hip arthroplasty, often known as hip replacement, is a surgical surgery used to treat hip pain. Artificial implants are used during the operation to replace some of the hip joint.
A hip replacement is major surgery and is typically only advised if other treatments, such as physiotherapy or steroid injections, have failed to relieve pain or improve function.
The hip joint is made up of a ball at the top of the femur, also known as the thigh bone, and a socket in the pelvis, also known as the hip bone.
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a nurse is assessing a client who is taking levothyroxine. the nurse should recognize that which of the following findings is a manifestation of levothyroxine overdose?
Overdosing on levothyroxine will cause hyperthyroidism symptoms as sleeplessness, tachycardia, and heat.
Constipation is a sign of hypothyroidism and indicates an inadequate dose of levothyroxine. Drowsiness is a symptom of hypothyroidism and indicates a too low dose of levothyroxine. Levothyroxine is a thyroid drug that replaces hormones normally produced by the thyroid gland to control the body's energy and metabolism. Hypothyroidism is treated with levothyroxine (lowering thyroid hormone levels). If your thyroid doesn't make enough of this hormone naturally, this drug is prescribed.The thyroid hormone thyroxine comes in a synthetic version called levothyroxine, sometimes called L-thyroxine. Used to treat thyroid hormone deficiency, especially severe myxedema, coma, and Hashimoto's disease.Therefore, levothyroxine causes a number of side effects.
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when reading a medication bottle, janet sees a warning label against taking this medication when pregnant. why might this warning be there?
The warning might be (2) Taking this medication could put the baby at a higher risk for birth defects.
Women who are expecting or nursing frequently worry about whether a medication they need for their personal health may harm their unborn child or whether their body is changing and a greater or lower dose is necessary.
Most people nowadays are aware that drinking alcohol and illicit substances while pregnant can result in severe developmental birth defects. However, taking some prescription medications while pregnant might result in birth abnormalities. Teratogenic medications are those that have the potential to result in birth abnormalities.
If a pregnant woman has a medical problem, stopping her prescription medication use might be risky. Without treatment, the mother's health and the wellbeing of her unborn child might be at danger.
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Question correction:
When reading a medication bottle, Janet sees a warning label against taking this medication when pregnant. Why might this warning be there?
1. Taking this medication could decrease the hormones sent to the baby.
2. Taking this medication could put the baby at a higher risk for birth defects.
3. Taking this medication could sent the mother into a depressive cycle.
4.Taking this medication while pregnant could render the medication ineffective.
comparative study of combination therapy with non-steroidal anti inflammatory drugs and different doses of low level laser therapy in acute low back pain.
In patients with acute low back pain, laser therapy combined with medication therapy was a more effective way to reduce pain and impairment than medication therapy alone, however the evidence for this conclusion is still insufficient.
65 patients were randomly divided into four groups for the current randomized, placebo-controlled investigation. Patients received only pharmacological therapy in group 1 (N = 20) and laser therapy (3 J/cm 2) in group 2 (N = 15) in addition to receiving medication.
A comparable treatment regimen to that of group 2 was administered to group 3 (N = 15), but the laser dose was 6 J/cm 2. Finally, group 4 (N = 15) received both medication therapy and a placebo laser treatment.
Using a visual analogue scale and the Oswestry low back pain disability questionnaire, pain levels were compared between the groups. Significant differences were found between baseline pain scores and those from the first, second, third, and fourth weeks of laser therapy in all intervention groups.
Additionally, the outcomes of the intergroup analyses demonstrated a substantial distinction between group 1 and groups 2 and 3. After laser therapy, there was a significant ODI difference between the groups.
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the nurse is explaining to a new graduate nurse about how to assess for pain in an infant. the nurse knows the teaching was effective when the graduate nurse identifies which symptom(s) as a sign of pain in an infant? select all that apply.
a. quivering chin
b. Diffuse body movements
c. inconsolability
d. clenched fists
e. tears
f. high-pitched cry
The following categories are most commonly used to classify infant development. Toddlers grow physically. For example, sucking is done before sitting and before walking. Infants up to 2 months of age: When lying on their back, they can raise and turn their heads. Arms are bent and hands are clenched. When the baby is pulled into the sitting position, the neck can no longer support the head.Therefore, a number of symptoms will be observed in the infant.
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a nurse is caring for a client who received an injection of penicillin g procaine. the client begins to experience dyspnea and tongue swelling. which of the following actions should the nurse perform first?
Answer:
The client should be placed in a supine position with the head of the bed elevated to help improve their breathing. The nurse should then notify the physician about the client's reaction and start an IV of normal saline to keep the client hydrated.
Explanation:
The Explanation for this is that, when a person is having an allergic reaction, one of the first things that can help is to make sure that their airway is clear and that they are getting enough oxygen. Placing them in a supine position with the head of the bed elevated can help to improve their breathing. Notifying the physician is also important so that they can order the appropriate medication to help the client with their reaction.
a nurse has been hired to ooversee the operations of a sereis of ambulatory clincis the nurse can best promote
The nurse can best promote Integrating and management skills
The best way to foster success and high achievement is for individuals to combine their leadership and management responsibilities. While encouraging certain management competencies among staff members can be advantageous, it cannot take the place of the importance of the leader manager's own skill set. Followership must be corned rather than mancated. Due to conflicts, having numerous leaders might make it more challenging to enact change.
What is management skills ?An executive needs have certain qualities or skills in order to carry out specific jobs in an organisation, and these qualities or talents are referred to as management competencies. They include the ability to carry out executive responsibilities in an organisation while averting crises and quickly resolving issues when they arise.
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the nurse is explaining to a new graduate nurse about how to assess for pain in an infant. the nurse knows the teaching was effective when the graduate nurse identifies which symptom(s) as a sign of pain in an infant? select all that apply.
Since babies cannot verbally express their feelings, it can be challenging to tell if they are in discomfort, but there are indications that can help you recognize when they are. For instance, if a child is suffering:
Modifications to crying patterns. Sometimes, but not usually, a baby's disturbed cry sounds different from regular crying. Behavioral changes in your infant might sometimes be a warning sign. For instance, crying that is unaffected by a drink, a diaper change, or cuddling may indicate pain. Additionally, a normally quiet baby that becomes unusually fussy may be hurt.
Crying when giving birth. The infant who cries while being breastfed may very probably have an uncomfortable ear infection.
prolonged, strong crying that frequently occurs daily at the same moment. With colic, this behavior is typical. It frequently begins at 2 weeks old, peaks at 6 weeks, and then slowly drops.
crying while raising the legs to the stomach. Your infant might have colic or a serious illness.
Withdrawing. A baby's energy may be depleted by chronic pain, which may manifest as stillness, quietness, and avoidance of eye contact.
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when the nurse is evaluating the reliability of a patient’s responses, which of these statements would be correct? the patient:
To establish reliability, analysts look at consistency throughout time, inside the measurement device, and between different observers. The patient Provided constant communication and therefore is reliable.
How is dependability assessed?Analysts evaluate consistency throughout time, inside the measuring tool, and between various observers to determine reliability.Test-retest reliability, internal consistency, and inter-rater consistency are further names for these sorts of consistency. To assess test-retest reliability, the measure must first be administered to a group of participants and then administered to the same people again at a later date.The test-retest correlation between the two sets of scores must also be examined. This is often accomplished by creating a scatterplot of the data and calculating Pearson's r.The split-half, test-retest, internal consistency, and reliability coefficient are a few techniques for assessing the dependability of a research endeavor.Therefore, the correct answer is option b. Provided consistent information and therefore is reliable.
The complete question is:
When the nurse is evaluating the reliability of a patient's responses, which of these statements would be correct? The patient:
a. Has a history of drug abuse and therefore is not reliable.
b. Provided consistent information and therefore is reliable.
c. Smiled throughout interview and therefore is assumed reliable.
d. Would not answer questions concerning stress and therefore is not reliable.
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During childhood, an example of _______ occurs when the liver increases in size as hepatocytes undergo cell division.
During childhood, an example of Hyperplasia occurs when the liver increases in size as hepatocytes undergo cell division.
What is cell division?
When people talk about "cell division," they typically mean mitosis, which is the process of creating new cells for the body. The cell division process known as meiosis is what produces egg and sperm cells. A vital process for life is mitosis.
What is hyperplasia?
Cellular adaptations are changes in a cell's physiology, morphology, or number that occur during abnormal situations to adapt to the changing environment.
Hepatocytes in the affected area divide more frequently and go through "hyperplasia," which refers to these changes. Both compensatory and hormonal hyperplasia, in which the organs renew in response to hormones, are possible types of hyperplasia.
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association between diabetes medications and the risk of parkinson's disease: a systematic review and meta-analysis
The impact of various diabetes drugs on the risk of Parkinson's disease is unknown, and the quality of studies is poor. While our findings indicate a lack of relationship between metformin use.
Parkinson's disease
Parkinson's disease is a neurological ailment that produces unintentional or uncontrollable movements such as shaking, stiffness, and difficulties with balance and coordination. Symptoms normally appear gradually and progress over time. People may have trouble walking and talking as the condition advances.
What age does Parkinson's usually start?Age is a recognized risk: Although the majority of persons with Parkinson's disease develop the symptoms beyond the age of 60, about 5% to 10% develop the disease before the age of 50. Parkinson's disease with early onset is usually inherited, although not always, and some kinds have been linked to specific gene alterations.
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hipaa’s protections for health information used for research purposes…supplement those of the common rule and fda.only apply to research conducted inside covered entities.replace those of the
Hipaa’s protections for health information used for research purposes supplement those of the Common Rule and FDA.
The HIPAA Privacy Rule applies to health plans, health care clearinghouses, and other entities, and provides national standards to secure individuals' medical records and other individually identifiable health information (collectively, "protected health information").
It is necessary to have authorisation for study, or to fulfil one of the requirements for a waiver of authorization. Only with patient consent, or with a waiver, amendment, or exemption finding from an IRB or Privacy Board, may retrospective research studies be conducted. Remember, though, that you typically need permission from an IRB, privacy board, or other authorised regulating agency before moving forward on your own.
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a 30-year-old client presents to the clinic for an employment physical. the nurse notes protein in the client’s urine. the nurse understands that transient proteinuria can be caused by which factor(s)? select all that apply.
Nephrotic syndrome occurs when damage to the capillaries of the glomeruli causes proteins to leak into the urine.
What is Nephrotic syndrome ?Nephrotic syndrome typically results from inflamed glomeruli, which permit excessive protein leakage from your blood into your urine. The glomeruli in healthy kidneys allow the blood to keep the cells and proteins the body requires while filtering out waste items.
The majority of kids "outgrow" the nephrotic syndrome in their late teens or early adulthood, despite the fact that there is no known treatment for it. Some kids will only experience one episode of the syndrome.Learn more about Nephrotic syndrome here:
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dufendach kr, eichenberger ja, mcpheeters ml, temple mw, bhatia hl, alrifai mw, potter sa, weinberg st, johnson kb, lehmann cu. core functionality in pediatric electronic health records [internet]. rockville (md): agency for healthcare research and quality (us); 2015 apr. report no.: 15-ehc014-ef. pmid: 25950078.
Adding new pediatric functionality to an Electronic Health Record (EHR) should be done carefully, preferably taking usefulness, testability, and usability factors into account.
Electronic Health Record (EHR) is the collected patient data and health information stored digitally.
Experts agree in the literature that particular functions are needed in EHRs used in pediatric care in order to assist the work of child health care professionals and ensure the provision of high-quality treatment to pediatric patients. These capabilities are related to the maturing physiology and circumstances of a kid. The interaction between pediatric patients and their caregivers, including teenage privacy, as well as child development, physiologic drug dosage, pediatric illness treatment, and pediatric standards are among the key topics. The majority of pre-post research on a select few crucial capabilities provide the empirical evidence for health outcomes related to the adoption of a pediatric EHR or for the deployment of technologies like clinical decision support. If these features are properly implemented, according to key informants, the EHR will also help significantly in the treatment of all patients. The need to promote and sustain patient safety, the patient-centered medical home, and the growing prevalence of pediatric-specific clinical quality indicators are the current motivators for creating pediatric functionality for EHRs.
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the nurse is admitting a new patient and is collecting data through obtaining a health history and physical assessment. what phase of the problem-solving process is the nurse focusing on with the patient?
The phase of the problem-solving process on which the nurse is concentrating is the approach to problem solving, which is applicable to issues not related to patients.
What is Physical assessment?Vital signs, such as height, weight, blood pressure, breathing rate, and pulse rate, are often included in a conventional physical examination. Testing your far vision's sharpness or clarity is known as vision acuity. Exam of the head, eyes, ears, nose, and throat, including appropriate inspection, palpation, and testing.
The nurse is admitting a new patient and gathering information by getting a health history and performing a physical examination. What stage of the patient's problem-solving process is the nurse concentrating on?The nurse is concentrating on three phases of the patient's problem-solving process: implementation, evaluation, and assessment.
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effect of continued folic acid supplementa-tion beyond the first trimester of pregnancy on cognitiveperformance in the child: a follow-up study from a random-ized controlled trial
Folic acid tablets are given by doctors during pregnancy to avoid deficiency of anemia in the mother.
What is anemia ?The decrease in level of hemoglobin in body leads to anemia. The cognitive development of the unborn child may be benefited by continuing folic acid treatment during pregnancy after the initial window of time indicated to prevent NTD.
NTDs are neglected tropical disease. Hb is very important for transfer of essential gas like oxygen and carbon dioxide. It plays a important role in maintaining the blood level in the body. If hemoglobin level decreases it leads to anemia.
At the time of pregnancy doctors prescribe folic acid tablets to mother to prevent anemia in mother and child.
Therefore, Folic acid tablets are given by doctors during pregnancy to avoid deficiency of anemia in the mother.
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The stage of resistance of the general adaptation syndrome can rapidly lead to death. True or false
The general adaption syndrome which can rapidly lead to death called as stage of resistance is the false statement. The true statement is that it is the stage of exhaustion.
General adaption syndrome, consisting of three stages:
alarm, resistance, and exhaustion.The body's immediate reaction to "perceived" stress is alarm, fight or flight. The resistance stage is when your body begins to mend itself and normalize heart rate, blood pressure, etc.
Your body enters this recuperation phase following the initial shock of a stressful event, but it continues to be on high alert for some time. The body has now used up all of its energy reserves while trying and failing to return to the original alarm reaction stage.
When stress reaches the exhausted state, a person's body is no longer capable of combating it.
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dystonia develops in a client receiving injections of fluphenazine decanoate for schizophrenia. which clinical manifestations would the nurse document during the assessment? select all that apply. one, some, or all responses may be correct. quizlet
Dystonia develops in a client receiving injections of fluphenazine decanoate for schizophrenia the nurse document during the assessment would be Torticollis and Oculogyric crisis.
Briefing :Fluphenazine decanoate can have the adverse effect of altered or impaired muscular tone, or dystonia. Dystonia is characterized by neck spasms that cause torticollis, which pulls the head to one side. Oculogyric crises, or eye deviation and fixation, are symptoms of dystonia. Dystonia is unrelated to the sensation of agitation and an urgent need to move (akathisia). Pseudoparkinsonianism is characterized by a shuffling stride. Pseudoparkinsonism is also characterized by a mask-like facies.
Dystonia :Uncontrollable muscular spasms that result in recurring or twisting motions.
One or more body parts, and even the entire body, may be impacted by dystonia. It might either be minor or severe.
Involuntary muscle contractions that cause cramping, slow, repeated movements, or aberrant posture are the predominant symptom.
Medicines, injections, and physical therapy are all possible treatments.
Is dystonia a form of Parkinson's?In addition to being a movement condition on its own, dystonia can be a sign of Parkinson's disease and a few other illnesses. A foot turning inward or a head tilting to one side are examples of aberrant movements and postures brought on by painful, protracted muscle contractions.
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budesonide/formoterol in a single inhaler for maintenance and relief in mild-to-moderate asthma: a randomized, double-blind trial. chest. 2006
To compare a novel asthma management strategy--budesonide/formoterol in a single inhaler for both maintenance therapy and symptom relief--with a higher dose of budesonide plus as-needed terbutaline.
What is the result of the above study ?Greater improvements in morning PEF were seen in patients receiving budesonide/formoterol compared to those receiving budesonide (increases of 34.5 L/min vs 9.5 L/min, respectively; p 0.001). With budesonide/formoterol compared to budesonide, the probability of experiencing a severe exacerbation (hospitalization/emergency department [ED] treatment, oral steroids for asthma, or a > or = 30% reduction from baseline in morning PEF on 2 consecutive days) was 54% lower (p = 0.0011). Patients taking budesonide/formoterol had 90% fewer hospitalizations and ED visits for asthma (1 vs. 10, respectively; p = 0.026). The enhanced efficacy with budesonide/formoterol was obtained with 77% fewer oral steroid treatment days compared to the budesonide group and with less ICS (mean dose, 240 microg/d vs 320 microg/d, respectively) (114 days vs 498 days, respectively). Both therapies worked out well.
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