sayed, k., et al., dish simulator: capturing dynamics of cellular signaling with heterogeneous knowledge, in proceedings of the 2017 winter simulation conference. 2017, ieee press: las vegas, nevada. p. 1-12

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Answer 1

Capturing dynamics of cellular signaling with heterogeneous knowledge, in proceedings of the 2017 winter simulation conference DiSH simulator.

We introduce DiSH-Sim, a large discrete model simulator for biological signal transduction pathways that can simulate multi-valued network elements in both deterministic and stochastic methods. Because biological processes are not synchronised and some biochemical changes take longer to occur than others, we place a strong emphasis on updating in the correct order and including temporal information. The usage of grouped rules to simulate multi-valued items and delays is another aspect of our simulator. The DiSH-Sim is used to validate discrete cancer microenvironment and infectious illness models and is openly available. Additionally, it is a part of a sizable infrastructure that has natural language processing tools for reading biological literature and constructing logical models.

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Related Questions

In what sense are nutrients from a recently ingested meal not really "inside" your body prior to the absorption stage of food processing?

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Nutrients will remain in the alimentary canal cavity as long as they are in a space that is continuous with the outside environment through the mouth and until they pass a membrane to enter the body.

How Does the Stomach Digest Food?You are unaware of the carefully planned series of actions that occur inside your body as you chew and swallow. Involuntary muscle contractions known as peristalsis are responsible for moving food through your digestive system. Food travels down your food pipe in the initial phase of this voyage (esophagus). It travels from your throat to your stomach in this way. Inside your stomach, food undergoes a sizable portion of the digestion process. Several digestive fluids and enzymes are produced in the stomach and mix with the food. The stomach's powerful muscles then work like a blender to transform food into a form that can be consumed. The contents of the stomach gently move into a little tube at the base of the stomach once it has finished its job in the digestive process. It is known as the duodenum. It is the small intestine's beginning. The subsequent phase of digestion occurs here. Food is converted into energy by the digestive juices produced in organs like the liver and pancreas.

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the complex set of cells, chemicals, and processes that protects the body against pathogens when they succeed in entering the body is known as the

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This set of elements is known as the immune system.

How can we describe the immune system?It is the system that defends the organism.It is a system that fights the entry of foreign bodies into the body.It is the system that fights bacteria, viruses and other microorganisms that can cause disease.

As was shown in the question above, the immune system is made up of a complex of cells, chemicals and processes. The purpose of the immune system is to protect the body from any threat and for this it uses the thymus, spleen, lymph nodes, tonsils and cells called white blood cells and macrophages.

For the immune system to reach its goal it must be fortified and this fortification is done with a balanced diet, exercises and beneficial behaviors.

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a negative feedback loop is a process in which the body senses a change and activates mechanisms to reverse that change. group starts

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A negative feedback loop is a process in which the body senses a change and activates mechanisms to reverse that change. This is false.

When it comes to feedback loops, there seems to be a lot of confusion out there. So let's set the record straight: a negative feedback loop is NOT a process in which the body senses a change and activates mechanisms to reverse that change.

What is a negative feedback loop then? Well, it's simply a process whereby the body responds to a change by creating an opposing force that counters the original change.

For example, let's say your body temperature starts to rise. This increase in temperature is detected by the brain, which then signals the body to sweat. The sweat then helps to cool the body down, reversing the original change (increase in temperature).

So, in short, a negative feedback loop is a process that helps the body maintain homeostasis (a state of balance).

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In endospore formation, when dna condenses and aligns itself in the center of the cell, the cell is called a:_____.

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In endospore formation, when dna condenses and aligns itself in the center of the cell, the cell is called a: mother cell

Mother cells are known as the raw material of the body because from it all other cells are generated, this happens when the mother cell undergoes its division process.

What is a cell?

A cell is the most basic and smallest form of life that exists in a living being, its parts are the membrane, the cytoplasm and the organelles including the nucleus.

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Which interaction of water molecules results in cohesion and adhesion?
O ionic bonding
O nuclear bonding
O covalent bonding
O hydrogen bonding

Answers

Hydrogen bonding interaction of water molecules results in cohesion and adhesion.

A water molecule consists of two atoms of hydrogen related by using covalent bonds to the equal atom of oxygen. Atoms of oxygen are electronegative and attract the shared electrons in their covalent bonds.

Water molecules are certainly attracted and persist with each other because of this polarity, forming a hydrogen bond. This hydrogen bond is the purpose at the back of lots of water's special properties, along with the fact that it's denser in its liquid state than in its strong state (ice floats on water).

A water molecule includes hydrogen atoms bonded to an oxygen atom, and its standard structure is bent. this is due to the fact the oxygen atom, in addition to forming bonds with the hydrogen atoms, also consists of pairs of unshared electrons. all of the electron pairs—shared and unshared—repel each different.

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He nurse reviews a patient's cardiopulmonary health history and identifies that which diagnosis impacts cardiac oxygenation?

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Angina pectoris diagnosis impacts cardiac oxygenation.

Angina pectoris- Angina is a cardiac disorder brought on by a lack of blood flow to the heart muscle. This is often brought on by the hardening and narrowing of the arteries supplying the cardiac muscle. The syndrome is typical among elderly persons.

Oxygenation- Adding oxygen to a system, such as the human body. The term "oxygenation" also can refer to the procedure of administering oxygen to a patient or of mixing oxygen with a drug or other chemical.

Cardiac muscle- The myocardium, or cardiac muscle tissue, is a particular kind of muscular tissue that makes up the heart. This muscular tissue, which unconsciously contracts and relaxes, keeps the heart circulating blood throughout the body.

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How does the directionality of the polynucleotide chain affect how the chain is replicated and/or transcribed?.

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The directionality of the polynucleotide allow the base pairing in the chain that is replicated and/or transcribed.

A polynucleotide chain possesses directionality, or two ends that differ from one another, as a result of the structure of nucleotides. The 5' phosphate group of the chain's initial nucleotide protrudes at the 5' end, or commencement, of the chain. The 3' hydroxyl of the final nucleotide added to the chain is exposed at the opposite end, often known as the 3' end.

Typically, DNA sequences are written from 5' to 3'. Base pairing, which is necessary for both the replication and transcription of the genetic material, is made possible by the DNA double helix's two linked strands running in opposite directions. New copies of DNA and RNA nucleotide chains are created from the originals during replication.

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what are characteristics of the conducting passages of the bronchial tree as air moves from the primary bronchi to the alveolar ducts?

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The width of the conducting channels is smaller and there is less cartilage in the bronchioles.

Bronchioles- Smaller and smaller passages, known as bronchioles, branch out from the major airways (bronchi), leading to air sacs (alveoli).

Alveoli- Small air sacs near the bronchioles' ends (tiny branches of air tubes in the lungs). While breathing in and out, oxygen and carbon dioxide are exchanged between the blood and alveoli in the lungs.

Cartilage- The body's supporting connective tissue, cartilage, is a non-vascular form that may be found everywhere. Due to its avascularity and less ordered microarchitecture than bone, cartilage is a loose connective tissue that varies from bone in a number of ways.

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The________________________ variable in an investigation is the variable that is deliberately manipulated.​

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Answer:

The independent variable in an investigation is the variable that is deliberately manipulated.​

Explanation:

How many other organism types does each group eat in this food web? Which two groups are both predator and prey for each other?

Answers

Answer:

carnivores are predators, and herbivores—and sometimes omnivores or other carnivores—are their prey.

Explanation:

hihihhihijhvgvgcgctgu

Answers

Answer:

ok

Explanation:

a drug like nicotine that produces a biological response in the brain is called a(n) .

Answers

The drug like nicotine that produces a biological response in the brain is called agonist

An agonist is the drug that was activates certain receptors in the brain. the Full agonist opioids activate the opioid receptors was in the brain taht fully resulting in the full opioid effect. the Examples of the full agonists are the heroin, the oxycodone, the methadone, the hydrocodone, the morphine, the opium and others. Those molecules that bind to the specific receptors and cause the process in the cell to become more active are called as agonists. An agonist is something that can causes a specific physiological response in the cell. They can be natural or they are artificial. For instance, endorphins are the natural agonists of the opioid receptors.

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ford, m. c. et al. tuning of ranvier node and internode properties in myelinated axons to 635 adjust action potential timing. nat. commun. 6, 8073 (2015).

Answers

Axons that have undergone myelination are completely covered. Mammalian PNS axons range in size from 0.1 to 20 micrometres, with unmyelinated axons being less than 2 micrometres and myelinated axons being more than 1-2 micrometres. Nearly all axons in the CNS with diameters larger than 0.2 m are myelinated.

What is Axons?Axons, also known as nerve fibres, are the parts of a nerve cell (also known as a neuron) that carry nerve impulses away from the cell body.A neuron normally has one axon, which links it to other neurons, muscle cells, or gland cells.Some axons can be very long, extending, for instance, from the spinal cord to the tip of a toe.The majority of vertebrate axons are encased in myelin sheaths, which accelerates impulse transmission; some big axons may move at up to 90 metres (300 feet) per second.

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WILL GIVE BRAINLIEST
Which of the following is likely true of a coastal habitat?


Has low gross primary productivity

Speeds up the flow of the body of water

Located at the mouth of a river or stream

Sediment provides barriers that often serve as sanctuaries from wind and storms.

Answers

Sediment provides barriers that often serve as sanctuaries from wind and storms. Hope this helped ;)

Answer: The answer is D.

Explanation: Sediment provides barriers that often serve as sanctuaries from wind and storms. I got it right on the test :)

This gene encodes a protein and you would like to determine whether the protein localizes to the nucleus or the cytoplasm. how would you examine where the protein localizes in the cells?

Answers

Protein subcellular expression and molecular complexing interactions are correlated with their functional activities. With the use of fractionation techniques or fluorescence microscopy-based techniques, localization may be efficiently established.

When a signaling route is understood, it is possible to deduce a protein's function from its location. To comprehend basic biological processes, fluorescent proteins can be overexpressed inside of cells and recombined with either target proteins or regulatory areas.

Cellular protein localization is widely studied using fluorescence microscopy. Normally, time-consuming and error-prone conventional methods are used to assess images of protein sites. Therefore, automated methods are necessary for the categorization of such photos.

These techniques must be precise and efficient in terms of computing.

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I am a flowering plant in the mint family. You find me in many oils and perfumes. I am native to cape verde and canary islands. I am used in taking medicine. I am a herb. What plant am i?

Answers

Answer:

Lavandula

Explanation:

In what way can a vector of a zoonotic pathogen differ from a host of the pathogen?

Answers

A vector of a zoonotic pathogen differs from a host of the pathogen in that it is not affected by the pathogen.

What are vectors and pathogens?

Vectors are organisms which serve as carriers of disease-causing organisms known as pathogen. Vectors usually serve as transport or transit mechanisms by which diseases spread.

Pathogen are organisms that cause disease. A zoonotic pathogen is a pathogen that can move from non-human animals to humans.

The vector of a zoonotic pathogen differ from a host of the pathogen in that the vector is not affected by the pathogen and the vector is also non-human.

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What is the glycemic load (gl) of one cup of kidney beans, which contains 40g of carbohydrate and has a glycemic index of 24?

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The glycemic load (gl) of one cup of kidney beans, which contains 40g of carbohydrate and has a glycemic index of 24 is 9.6

The Glycemic load (GL) is worked out by the following formula: GL = GI x carbohydrate / 100 The Glycemic response  is actually a system of the assigning a number to carbohydrate-containing the foods according to how much each food has increases blood sugar. The glycemic index itself is not an diet plan but one of the various tools — such as the calorie counting or the carbohydrate counting most fruits and the vegetables, whole or the minimally processed grains, beans, pasta, the low-fat dairy products and the nuts. Foods with a GI of 56 to 69 come under the category of the moderate-GI foods. They include the potatoes, white rice, the corn, couscous and the breakfast cereals such as Mini-Wheats and the Cream of Wheat.

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Explain the interactions among organisms in pyramids of energy,numbers and biomas

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Answer:

Pyramids of energy show relative amounts of energy available at different trophic levels. Pyramids of biomass show the total amount of living tissue at each trophic level. A pyramid of numbers shows the relative numbers of organisms at different trophic levels.

Explanation:

The ________ and ________ are part of the respiratory system. bronchi, thymus lungs, esophagus alveoli, trachea testes, ovaries

Answers

Answer:

Alveoli, trachea

Explanation:

Lungs are part of the respiratory system, but the esophagus is part of the digestive system.

Bronchi and thymus are part of the lymphatic system.

Testes and ovaries are part of the respiratory system.

what is meant by ‘passive’ and ‘active’ cellular transport? what are some different types of channel proteins?

Answers

Active transport necessitates the movement of molecules, whereas passive transport does not necessitate the movement of molecules. Channel proteins are classified into two types: open channel proteins and gated channel proteins.

Which proteins are used in active and passive transport?

Carrier proteins, which change shape as they transfer their specific chemical across the membrane, are used in both passive and active transport. The sodium potassium pump and glucose exporters are two examples of carrier proteins found in our cells.

What are channel proteins and carrier proteins?

Channel proteins are proteins that can generate hydrophilic pores in cell membranes and transport chemicals along concentration gradients. Carrier proteins are integral proteins that can transfer molecules across the membrane in both directions, down and up the concentration gradient.

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Conn's syndrome is a condition caused by tumors of the adrenal cortex that secrete high amounts of aldosterone in an unregulated manner. What would you expect to be the major symptom of this disorder?

Answers

Hormones are secreted directly into the bloodstream by endocrine glands, without the use of a conduit. The major endocrine gland is the pituitary gland.

What is pituitary gland?

The pituitary gland is a tiny, pea-sized endocrine gland that is situated underneath the hypothalamus at the base of the brain. It causes the release of several crucial hormones and regulates the activity of numerous other endocrine system glands. The pituitary gland is hence known as the "master gland of all."

Adrenal cortical tumors that release excessive quantities of aldosterone erratically are the cause of Conn's syndrome. What primary symptom might you anticipate for this condition?

Conn's syndrome: Primary hyperaldosteronism is another name for Conn's syndrome.

This is caused by excessive aldosterone production, which is also demonstrated by a decrease in rennin secretion. The mineralocorticoid hormone aldosterone is essential for controlling the levels of K+ and Na+ ions in extracellular fluid and plasma, respectively. It is necessary for the distal tubule and collecting ducts of the nephron to reabsorb Na+ and excrete K+.

Aldosterone increases the reabsorption of Na+ ions while also stimulating the release of K+ ions by tubule cells.

Any change in the K+ ion concentration has the potential to impact the intracellular-extracellular K+ gradient. This causes cardiac muscles and neurons to become more excitable, which in turn causes an increase in heart rate, cardiac arrhythmias, and ultimately an increase in blood pressure.

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A manufacturing company dumps its wastes into a nearby pond. One of the wastes is found to paralyze the contractile vacuoles of certain protists. A biologist looking at individual samples of these organisms taken from the pond would find that they?.

Answers

Answer:

have gained water and burst.

According to corvino, if homosexual sex is wrong because it violates an organ's principal purpose, then?

Answers

It is not addressed in the studies on sex motives that people have sex because they ought to.

Sexual motivation, often known as sex drive, is the impulse to gratify one's sexual needs, whether directly through sexual activity or through seemingly unrelated hobbies (sublimation). The term "libido," initially used by Sigmund Freud to describe the universal desire for pleasure, one of the primary forces influencing behavior, was first coined by him. According to Freud, this urge was founded on genetics and connected to the need for the species to survive. Unlike other basic wants like hunger, the libido's satisfaction can be postponed or shifted without endangering a person's life. Sexual desires are therefore more likely to be suppressed in order to achieve socially acceptable goals.

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After a particle has been phagocytized, the vesicle in which it is contained fuses with a ______ which will then break down the particle into smaller components.

Answers

After a particle has been phagocytized, the vesicle in which it is contained fuses with a lysosomal vesicles which will then break down the particle into smaller components.

What are lysosomes?

Lysosomes are cellular organelles that contain digestive enzymes that will degrade the particle or nutrient that enters the lysosome. These will participate in many cellular processes, such as the destruction of viruses and bacteria, apoptosis and degradation of macronutrients.

Therefore, we can confirm that after a particle has been phagocytized, the vesicle in which it is contained fuses with a lysosomal vesicles which will then break down the particle into smaller components.

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can you help me with this?

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The most important element in living organisms is carbon and is found in all the four biomolecules; lipids, carbohydrates, proteins, and nucleic acids.

What is the role of carbon in living organisms?

Carbon is the most important element in living organisms.

Carbon is an element that is considered as the foundation of life. From this element comes 4 types of biomolecules. They are lipids, carbohydrates, proteins, and nucleic acids.

These biomolecules have building blocks that we call as monomers . Like a Lego, it acts like Lego the blocks to form each molecule. Carbohydrates monomer is called monosaccharides.  The Lipids monomer is composed of two. They are fatty acids and glycerol. Proteins also have monomer. It is called amino acids.

Our DNA is composed of chains of nucleic acids which also have nucleotides as its monomer. All biomolecules contain these 3 atoms or elements. They are carbon, hydrogen, and oxygen.

In conclusion, the four biomolecules lipids, carbohydrates, proteins, and nucleic acids are all composed of carbon, hydrogen and oxygen.

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Refers to how much land a species lives in:
O Local Population Density
O Habitat Tolerance
O Geographic Range
O None of these

Answers

Refers to how much land a species lives in Habitat Tolerance.

The tolerance ranges for abiotic environmental factors are similar to the geographic ranges that organisms have. To put it another way, they can tolerate (or survive in) a specific range of a given factor, but they cannot survive if the element is present in either an excessive or insufficient amount.

Let's quickly discuss the range of tolerance in biology, which is the variety of environmental conditions that a species may tolerate and still survive. To put it another way, having too little or too much of a certain environmental factor might be fatal.

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The symbol for resistance is the letter "R." What is the unit of resistance called?
Opposition
An Ohm
An ampere
A switch

Answers

Answer:

Hmm symbol for resistance is the letter "R." and the unit of resistance called?

I think its An ohm

Explanation:

The symbol: Ω is the unit of electrical resistance in the International System of Units.

The symbol: Ω means: Electrical resistance

So i think its B.

An Ohm

Hope this helped :)

if a cell starts out in g2 phase with 12 chromosomes, how many chromosomes would you expect in each of the daughter cells if one of the chromosomes failed to separate in anaphase? remember that if two chromatids are still attached at the centromere (as they would be in this case), we count them as one chromosome.

Answers

If a cell has 12 chromosomes when it enters the g2 phase, one daughter cell will have 11 and the other will have 12.

Describe chromosomes:

A chromosome is a long DNA molecule that houses all or some of the genetic code of an organism. Histones, which act as packing proteins for most eukaryotic chromosomes, collaborate with chaperone proteins to bind to and condense the DNA molecule to maintain the molecule's integrity.

What are the two purposes of chromosomes?

Chromosomes are made of proteins, primarily histones and DNA.

Chromosomes have a specific purpose.

Transporting genetic material from one generation to the next is the main function of chromosomes.The processes of growth, reproduction, repair, and regeneration all depend on chromosomes and are essential to their survival.

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The Krebs cycle forms many products. Which option lists the correct products of the Krebs cycle after 1 molecule of glucose goes through it? (1 point)
6 NADH, 2 ATP, 4 CO2, and 2 FADH₂
net 2 NAD+, 2 ATP, 4 CO₂, 2 FADH
O net 4 NADH, 4 ATP, 8 CO₂, 4 FADH₂
O net 1 NADH, 1 ATP, 2 CO₂. 1 FADH₂

Answers

The Krebs cycle will form as a product: 6 NADH, 2 ATP, 4 CO2, and 2 FADH₂

What is the Krebs cycle?

The Krebs cycle is a process in which the complete oxidation of metabolic fuels to CO2 occurs through a series of cyclic oxidative reactions. All the enzymes of the cycle will be located in the mitochondria and this will coincide with the location of the pyruvate dehydrogenase complex and beta oxidation enzymes, which are the main sources of acetyl-CoA. One of the functions of the cycle is the generation of reducing equivalents that are used to generate ATP in the sequence of electron transport and oxidative phosphorylation.

Oxidation of acetyl-CoA occurs in four reactions that transfer electrons to the coenzymes NAD or FAD. In other reactions of the cycle the bonds are rearranged to facilitate this transfer.

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What effect does a 300 mosmolar solution of a non-penetrating solute have on a cell, and how does this differ from the effect of a 300 mosmolar solution of a penetrating solute? TJ invested $4000 in a bond at a yearly rate of 2%. He earned $200 in interest. How long was the money invested consider cases where the number of withholding allowances is less than 6. which will cause the amount of federal income tax withheld to increase? very important please help due today please Jackson enjoys seeing the end result of his hard physical labor. the interest area that he should consider careers in would be _____. a. business b. crafts c. science d. office operations please select the best answer from the choices provided a b c d The contraction of muscle cells requires the chemical breakdown of atp into adp, which releases energy for the cell. what type of molecule lowers the activation energy required to start the breakdown of atp 3 Examples of Radiation 1. 2. 3. which model suggests that corporate social responsibility is composed of economic, legal, ethical, and philanthropic responsibilities that are built upon a firm's economic performance? Which of the following is NOT an economic responsibility of starting a sole proprietorship?O obtaining a business licenseO getting a site permitO registering a business nameO quickly selling off selling company stocks brook has 3,250 in her savings account. she plans to save an additional 175 each month. Brook wrote a linear function to represent y, the total amount of savings after x months. what did she do wrong?4= 175(x + 3,250) What is the quotient of (56) (4) 7?What is the quotient of (56) (4) 7? what did these migrations have in common: prehistoric people of central asia moved to north america during the last ice age. early people of the middle east moved into northern mesopotamia Read pages 5-6 of the story. What do the characters do during this event? (1 point) The girls find out that they have more in common than they thought. The girls find out that they have more in common than they thought. The girls find out they are really different from one another. The girls find out they are really different from one another. The girls find out that they both work very hard. The girls find out that they both work very hard. The girls find out that their parents are very similar. You start a savings account with $200 and save $30 each month. Let f(n) be the amount in the account before the nth month. How much money will you have invested at one year? Flash memory is a type of _____________ memory. a) Primary b) RAM c) Secondary d) All of these QuestionRefer to Explorations in Literature for a complete version of this story.In The Pit and the Pendulum, the narrator explains, "I proceeded for many paces; but still all was blackness and vacancy."How does Poe's inclusion of this description affect the story?It creates dark humor by making readers imagine how foolish the narrator must look in this situation.It creates dark humor by making readers imagine how foolish the narrator must look in this situation.It increases the suspense by maintaining the narrator's sense of displacement and uncertainty.It increases the suspense by maintaining the narrator's sense of displacement and uncertainty.It contributes to the story's rather serene mood by describing the peaceful emptiness of the environment.It contributes to the story's rather serene mood by describing the peaceful emptiness of the environment.It adds mystery to the tale by subtly suggesting that the narrator has something to hide.It adds mystery to the tale by subtly suggesting that the narrator has something to hide.Skip to navigation Choose an equivalent expression for two thirds to the fourth power times two thirds raised to the third power comma all raised to the second power.A. four ninths raised to the fourteenth powerB. four ninths raised to the twenty fourth powerC. two thirds raised to the fourteenth powerD. two thirds raised to the twenty fourth power determine the number of valence electrons in each of the following neutral atoms carbon nitrogen oxygen iodine Dr. dequincy investigates memory among adults aged 65 and older. based on the text, the most specific term for dr. dequincy's area of study is? pls help What is the sum? will mark brainiest47+ 85