linde, j., et al., data-and knowledge-based modeling of gene regulatory networks: an update. excli journal, 2015. 14: p. 346

Answers

Answer 1

The sentence is a part of a study about the Interactions between genes with the help of high-throughput data which were predicated by the gene regulatory network inference which is the biology system approach.

The updated network inference methods were presented on unexplored techniques for network inference assessment, data acquisition network inference for the integration of prior knowledge and interacting species. After the next generation, sequencing of cDNAs was derived from the RNA samples, there were applications in the network interference, there was a progression for both large-scale and small-scale genomic and condensed network inference, and advances were examined in the network inference methods because of crowdsourcing. There was current availability of prior knowledge sources and there was a perspective that recalls interacting species for the interference of the gene regulatory networks.

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Related Questions

A suggested explanation that might be true and is subject to testing by further observations is a(n)?

Answers

A suggested explanation that might be true and is subject to testing by further observations is called a hypothesis.

What is a hypothesis?

A hypothesis is a given explanation of a question that emerges by observing some phenomena form the real world, which can be tested (either confirmed or rejected) by using the experimental procedure of the scientific method.

Hypothesis can be tested by either experimental procedures or observational methods, which allows obtaining empirical evidence to make predictions.

In conclusion, a suggested explanation that might be true and is subject to testing by further observations is called a hypothesis.

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What is the term used to refer to the type of anthropology that focuses on the study of ancient human ancestors?

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The term used to refer to the type of anthropology that focuses on the study of ancient human ancestors is paleoanthropology.

We can simply describe anthropology as a branch of science that focuses on every aspect of humanity. Anthropology includes the study of human ancestors, the particular behaviors of humans, social cultures and norms, etc.

We can describe paleoanthropology as a branch of anthropology that focuses on the evolution of humans. Paleoanthropology deals with studying human ancestors through pieces of evidence such as fossil records. Under paleoanthropology, only those taxa are studies through which humans are known to have evolved. All the extinct primates, the evolution of which, gave rise to today's human are studied under this branch of anthropology.

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One of the opponents of the movie monster Godzilla is Mothra, a giant mothlike creature with a wingspan of several dozen meters. The largest known insects were Paleozoic dragonflies with half-meter wingspans. Focusing on respiration and gas exchange, explain why giant insects are improbable.

Answers

The main reasons why giant insects are improbable is because Insects have a tracheal system for gas exchange.

With this in mind, the tracheal system has to do with the respiratory system in which oxygen and carbon dioxide move primarily through air-filled tubes called tracheae and allows the insect to breathe.

As a result of this, giant insects are improbable because when the insect grows bigger, the tracheal system becomes longer and would take a long time to get to the central tissues and when this happens, the insect dies.

What is an Insect?

This refers to the small arthropod animal that has six legs and generally one or two pairs of wings.

Hence, we can see that The main reason why giant insects are improbable is that Insects have a tracheal system for gas exchange.

With this in mind, the tracheal system has to do with the respiratory system in which oxygen and carbon dioxide move primarily through air-filled tubes called tracheae and allows the insect to breathe.

As a result of this, giant insects are improbable because when the insect grows bigger, the tracheal system becomes longer and would take a long time to get to the central tissues and when this happens, the insect dies.

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what happens in convergent evolution? two distantly related species independently develop similar traits. separate species develop from a single ancestral species. species have similar traits that they inherited from a common ancestor. different species unite into a single species by interbreeding.

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Convergent evolution Two distantly related species acquire similar traits independently is correct answer

Convergent evolution in evolutionary biology is the evolution where two species that are not related to each other but developed similar traits independently due to having same ecological niche and environmental conditions. For example, wings of insect and birds.

Convergent evolution is When species have very different characteristics, but share a common ancestor. Similar structure, different function.

Small changes observed in a population across a geographical range that matches the concept of gradual divergence that, over time could lead to the formation of a new species is known as Continuous variation

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What is the Monomer for a Carbohydrate?
A: Nucleotide
B: Disaccharide
C: Monosaccharide
D: Polypeptide

Answers

Answer:

C

Explanation:

a monosaccharide behaves as a monomer of carbohydrates and polysaccharides are polymers of carbohydrates

Answer: b monosaccharide

Bacteria as a group are incredibly metabolically diverse, but individual species are often highly specialized to reduce competition in their natural environment. This results in these species being unculturable because.

Answers

Bacterial species are unculturable because their growth may depend on necessary growth factors provided by other organisms in their natural environment.

Bacterial culture is a method to allow growth or proliferation of bacteria on a culture medium under controlled laboratory conditions. Bacterial species are metabolically diverse but some of the species are highly specialized to reduce competition with other species in the environment. They can be cultured under in-vitro conditions. The two types of culture media include complete media and minimal media. Complete media provides all the nutrients and conditions required for bacterial growth while minimal media provides only the certain conditions.

Bacteria generally grow naturally in favourable conditions provided by the environment. In-vitro culturing of bacteria may not allow it to grow because of unfavourable conditions. Some reasons behind bacteria being unculturable include: the culture medium does not provide the essential nutrients, the culture medium is toxic to the bacterial growth, or some bacteria in the culture produces some substances that inhibits the growth of the target bacteria.

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Unlike adults, newborn babies ________. have a limited sense of smell cannot detect human faces prefer unfamiliar voices to familiar ones see unclearly across a wide range of distances

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Unlike adults, newborn babies cannot see clearly across a wide range of distances.

A new child babies is a proper or specialised synonym for the common time period little one, which means the very more youthful offspring of people. The term can also be used to consult juveniles of different organisms. a brand new toddler is, in colloquial use, an toddler who is only hours, days, or as much as at the least one month antique.

A newborn babies seem to on the whole sleep, consume, cry and champagne. but as you and your infant get to recognize each extraordinary and bond in your early days together, your day may even contain cuddling and playtime.

A new child infants care includes assessment for the need of resuscitation, a whole bodily examination, management of prophylactic drugs and vaccines, correct enough feedings, secure sleep, hygiene of the newborn, and unique essential areas for infant well being.

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When any object is observed under the microscope, which objective lens should be used first and why?.

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Answer: The 4x objective lens has the lowest power and, therefore the highest field of view.

The knee is ___ to the ankle. a) distal b) proximal c) superior d) inferi

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The knee is proximal to the ankle. The knee is proximal to the foot. Moving distally from the hip brings you to the thigh. The foot is distal to the knee. The pores and skin is superficial to bone

Tibia (shin bone) – runs from the knee to the ankle. The pinnacle of the tibia is made from  plateaus (or flat surfaces) that are protected in articular cartilage (inside the knee joint).The hips are (advanced or inferior) to the shoulders. The shoulders are (medial or lateral) to the spine. The knee is (distal or proximal) to the ankle. The knee is (advanced or inferior) to the ankle.

So a finger is distal to the wrist, that's distal to the elbow, that's distal to the shoulder. Or, similarly, the femur is proximal to the knee, that's proximal to the ankle, that's proximal to the toes.Distal manner further from the starting place of a frame component or the factor of attachment of a limb to the frame trunk. In this case, due to the fact the thigh is towards the frame trunk than the knee, the knee is distal (now no longer proximal) to the thigh.

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For vaccination against mycobacterial diseases such as tuberculosis (intracellular pathogen), the most important facet of the immune response to be stimulated is?

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The most important facet of the immune response to be stimulated is the Th1 inflammatory response.

What is the Th1 inflammatory response?It is the main element of the immunologic system to fight mycobacterial diseases.It is the element that drives the mycobacterial agent against macrophages.

Macrophages are defense cells that fight microorganisms quickly and efficiently, with the help of other cells.

For macrophages to act correctly, pathogens must be directed toward them. In this case, the Th1 inflammatory response is the most important element of the system to assume this responsibility.

This is because the Th1 inflammatory response is responsible for fighting the pathogen and signaling its presence to other defense cells.

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A glacier is decreasing its length. This means that its glacial budget is ...

a. positive
b. negative
c. neutral

Answers

Answer: b. neutral

Explanation:

Which theory has contributed the most to disprove the concept of blending inheritance?

Answers

The theory of Mendelian inheritance has contributed the most to disprove the concept of blending inheritance.

Mendelian inheritance describes about how the genes are transferred from the parents to the offspring. Mendel worked upon the pea plants to give his theory. He stated that the traits are passed on in the form of discrete unit which he called them factors. Later these were named genes. He gave the lay of segregation and the law of independent assortment and a hypothesis of dominance.

Blending inheritance says that the traits that are transferred to the offspring are the intermediate form of both the parents. However, the theory was disproved later.

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Dna is often described as having a shape like a spiral staircase. consider the photos. which of the spiral staircases in the photos is the better analogous representation of a dna molecule?

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Staircase with rail on both sides is the better analogous representation of a dna molecule.

What is the term for the DNA molecule's spiral shape?In terms of genomics, the structure of DNA is referred to as a "double helix." Two interwoven strands that spiral around one another to resemble a twisted ladder in a helix-like structure make up a DNA molecule. The backbone of each strand is made up of alternating deoxyribose and phosphate groups.Deoxyribose and phosphate groups alternately form the backbone of each strand. Each of the four bases—adenine (A), cytosine (C), guanine (G), and thymine (G)—is related to one of the sugars (T). Adenine and thymine establish a chemical link with cytosine and guanine, respectively, to join the two strands.

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as ambient temperature decreases, metabolic rate in an ectotherm decreases to maintain body temperature

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Metabolism is slow and heat is generated. Endotherms use metabolic heat to maintain a stable body temperature, but not exogenous heat.

An animal's "baseline" metabolic rate  is measured as the basal metabolic rate (BMR) for endotherms or as the standard metabolic rate (SMR) for exotherms. Among endotherms, smaller animals tend to have higher  basal metabolic rates per gram than larger animals (“hotter” metabolism). The same applies to external temperature, although groups cannot be compared. Your metabolic rate depends on your activity level. A more active animal has a higher metabolic rate than a less active animal. Some animals go into a state of lethargy where their metabolism slows down. Winter hibernation and  summer hibernation are forms of lethargy.

Ectotherms, however, lower their metabolic rate as the outside temperature drops in order to preserve body temperature.

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Children who have had an entire cerebral hemisphere removed are able to function well. this best illustrates the value of?

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This further illustrates the value of brain plasticity.

What is brain plasticity?It's the malleability of the brain.It is the brain's ability to adapt.

The brain is an organ with a lot of plasticity, which is the ability to adapt to different situations and show development and learning in the most different situations.

This allows people of all ages who have had a hemisphere of the brain removed to show a certain level of development and learning within the limitations. That's because the brain adapts and transforms into a functioning system even if a part of its structure is missing.

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Please help me. :)

3. what is the independent variable : is the one that is being chanted, which is the baking powder,


what is the Dependent variable: is the variable affected by the change, which is if the cookies will rise more


2 things that must remain constant for this experiment, is the temperature of the room, and the baking powder (you could make these up, for example you could say they have to be made in the same environment,)


4. write a hypothesis for this experiment


if.....

then.....

because.......

Answers

The hypothesis must reflect the relationship between the independent and the dependent variables. If a higher amount of baking powder is used to make the cookies, they will rise more because more carbon dioxyde is released.

What are the variables involved in an experiment?

Independent variable

This is the one the researcher changes to observe how this change affects the response of another variable.

Dependent variable

This is the variable that is affected by any change in the independent one. The dependent variable will respond by showing a change in its state.

Controlled variables

These are all the remaining variables in an experiment that must be kept under control to avoid a potential effect on the results. Usually, there are several controlled variables and the researcher must keep them stable so they can not influence the dependent variable.

What is a hypothesis?

The hypothesis is a prediction about what the researcher thinks might be going on or expects to occur.

It is a claim in which the researcher states a direct and clear relationship between the dependent and the independent variables.

Usually this relationship is a cause and consequence effect, so the way it is usually written is as follows,

"If.... (independent variable), then .... (dependent variable response)"

To answer the question, since I do not have a background, I will assume the following, (note: I advise you check if this assumption is correct with your problem statement)

The goal of the experiment is to see if the amount of baking powder used to make cookies will make them rise more.

Treatment groups: two cookie masses using two different baking powder quantities.

Control group: one cookie mass using no baking powder.

The same amount of water and the same amount and type of flour was used to prepare the three masses.

Treatment groups were exposed to the same type of baking powder.

The three masses were placed in a room under the same temperature.

Variables,

Independent variable ⇒  amount of baking powder (amount nº 1 and nº 2)Dependent variable ⇒ cookies rising Controlled variable ⇒ room temperature, water amount, flour amount and type, baking powder type, etcetera.

Hypothesis: Here I propose two possible hypothesis with the same idea.

1)

If a higher amount of baking powder is used to make the cookies, they will rise more because more carbon dioxyde is released.

2)

If amount nº 2 of baking powder is used to make the cookies, they will rise more than using amount nº 1 because there is more powder acting on the mass.

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When researchers allowed normal cortical rotation to occur, and then forced the opposite rotation, the result was a twoheaded embryo. How might you explain this finding, thinking about how cortical rotation influences body axis formation?

Answers

Segregation of cortical turns and maternal gene products in cleavage-stage embryos.

A. Direction of early cell division. The first level of cleavage is determined by the sperm entry point (SEP) and the vegetative axis (A-V). The second split is orthogonal to the first but still includes the AV axis. The dorsal blastomere is defined in the hemisphere opposite the SEP. The third section is slightly above the equator. Replacement of the maternal gene product. Eggs contain nutritionally localized maternal gene products. At fertilization, a microtubule network is established and the outer layer or cortex of the unicellular embryo rotates to push the cortical regions of the plant away from her SEP. Maternal gene products migrate to the dorsal hemisphere presumably by motility or vesicular transport with the cortex and are further segregated by subsequent cell division. Oocyte polarity and embryo patterning are well-established hallmarks of development in lower species. Whether a similar form of prestructuring exists in mammals is currently the subject of intense debate in mice. This study examined this issue in sheep for the first time as a large mammalian model. Microsurgical trisection of her unfertilized MII oocyte revealed

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many gene sequences that are involved in gene regulation contain a conserved sequence. this means that:

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Many gene sequences that are involved in gene regulation contain a conserved sequence this means that, the conserved sequence that have same gene sequence can be present in the variety of organism they can be same or different species.

The conserved sequence means a base sequence in the DNA that cannot be changed throughout evolution. This means that the large protein structure, amino acids, sequence region were identified.

The conserved sequence of the DNA does not code protein, these are non-coding region of the DNA sequence. These conserved sequence required for the basic cellular stability, function and reproduction.

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______ are concentrated primarily outside of the neuron, in the extracellular fluid, which contributes to the negative resting membrane potential of neurons.

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Chloride ions are concentrated primarily outside of the neuron, in the extracellular fluid, which contributes to the negative resting membrane potential of neurons.

What is the negative resting membrane potential?

The negative resting membrane potential refers to the negative net charge of certain cells due to differences in the concentration of ions on both sides of the cell membrane.

In conclusion, chloride ions are concentrated primarily outside of the neuron, in the extracellular fluid, which contributes to the negative resting membrane potential of neurons.

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What percentage of the energy in the caterpillar's food is actually used for secondary production (growth)?

Answers

The percentage of the energy in the caterpillar's food that is actually used for secondary production growth is 17%.

It is miles used for metabolic processes or given off to the environment as heat. This lack of electricity explains why there are rarely greater than trophic ranges in a meals chain or internet.

Strength is regularly misplaced inside the shape of heat and isn't completely to be had after transfer. The caterpillar's food ecological implication of the concept is that no strength is transferred due to the fact electricity is normally misplaced inside the shape of warmth and it it is always absolutely available after the switch.

The waft of power from one trophic degree to every other trophic degree within the meals chain is defined inside the pyramid of energy. consistent with percent regulation, of the captured energy is lost as heat inside the preceding level and the handiest 10% is available for the next degree.

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Disclaimer:- your question is incomplete, please see below for the complete question.

Approximately what percentage of the energy in the caterpillar's food is actually used for secondary production (growth)?

17%

34%

50%

100%

a central theme of hominin evolution is a(n) a. decreasing body size. b. decreasing cranial capacity. c. increasing adaptive flexibility. d. more robust jaw.

Answers

A central theme of hominin evolution is an: (c) increasing adaptive flexibility.

Hominin are the tribe that belong to the subfamily Homininae. The only member alive from that tribe today are Homo sapiens. The characteristics of Homininae are: erect posture, bipedal locomotion, larger brains, and communication using language. Hominins are more close to humans even than the chimpanzees.

Adaptive flexibility is the ability to adapt according to changing situations and environment. The organisms that possess great adaptive flexibilities are able to survive better in the ever-changing environments. They have the potential to develop strategies to cope up with the situation.

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Which component of clients nephron as a receptor site for the anitdiuretic hormone to regulate water imbalance?

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Antidiuretic  hormone binds to receptors on cells in the collecting ducts of the kidney and promotes reabsorption of water back into the circulation.

What effect does antidiuretic hormone ADH have on the nephron ?

ADH secretion is regulated by plasma osmolality. If plasma osmolality increase , it stimulates secretion of ADH , which acts at the collecting duct of the nephron where it causes reabsorption of only water and produces concentrated urine.

The receptor of ADH in the basolateral membranes of cells in the cortical and medullary collecting tubules and not on the apical membrane.

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One factor that could account for a rise in the water table is:
A. more wind.
B. more precipitation.
C. more clouds.
D. less porous soil.
SUBMIT

Answers

BBBBBBBBBBBBBBBBBBBBBBB

Which option is an example of entropy?
O A caterpillar develops into a butterfly.
Biological compounds come together to form an organism.
O A molecule is formed from atoms bonding together.
A tree dies and decomposes over time.

Answers

Answer:

A Tree Dies Over Time

Explanation:

Btw I cant really explain it well so

A tree dies and decomposes over time is an example of entropy. Therefore, option (D) is correct.

Entropy is a concept in thermodynamics that refers to the measure of the disorder or randomness in a system. In the context of the options provided, the process of a tree dying and decomposing over time is an example of entropy. As the tree decomposes, its complex organic matter breaks down into simpler compounds, and the overall system becomes more disordered and randomized.

Entropy tends to increase over time in natural processes, leading to a more disordered and less organized state. In the case of the decomposing tree, the once structured and organized tree gradually breaks down, and its components disperse and mix with the environment, increasing the overall disorder in the system. This example illustrates the principle of increasing entropy observed in various natural processes. Therefore, option (D) is correct.

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Can the dorsal lip of the blastopore induce cells in another part of the amphibian embryo to change their developmental fate?

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When transplanted, the dorsal lip of the blastopore—the region destined to give rise to the dorsal mesoderm—not only did not alter fate, but also caused the host cells around it to do so.

Hans Spemann and his graduate student Hilde Mangold carried out the crucial experiments in 1924. They discovered that when transplanted to an ectopic host site, one area of the late blastula and early gastrula functioned in an exceptional manner. When transplanted, the dorsal lip of the blastopore—the region destined to give rise to the dorsal mesoderm—not only did not alter fate, but also caused the host cells around it to do so. The dorsal lip transplant dramatically altered the fate of the embryo, inducing a brand-new developmental axis. Because of its distinctive inductive properties, the dorsal lip of the blastopore was given the moniker "organizer".

Therefore, Cells in another area of the amphibian embryo are induced by the dorsal lip of the blastopore to modify their course of development.

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Keystone species can have significant influences over several populations in a community through:____.

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Keystone species can have significant influences on several populations in a community through the effect of high amounts of biomass and energy transfer between populations.

A keystone species is a type of organism that defines the whole ecosystem and hold together the complicated network of relationships between the organisms.

These species have immense importance in an ecosystem and serve as the key drivers of the entire system.

Without these species, the ecosystem would stop dramatically or cease to exist at all.

Undoubtedly, they have less function redundancy yet the maximum impact on the working and existence of the entire ecosystem.

They can be plants, animals, or microorganisms, for example, elephants, sea otters, and wolves.

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_____ tend to be around zero, suggesting little direct environmental influence on the traits of extraversion and neuroticism.

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D)Correlations between adopted children and their biological parents tend to be around zero, suggesting little direct environmental influence on the traits of extraversion and neuroticism.

Neuroticism is a trait that displays someone's level of emotional balance. it's miles regularly described as a bad personality trait involving negative feelings, bad self-regulation, trouble coping with pressure, a strong response to perceived, and the tendency.

Neuroticism is related to misery and dissatisfaction. Neurotic individuals  have a tendency to feel disappointed with themselves and their lives. they are much more likely to record minor health troubles and to experience fashionable pain in a extensive variety of situations.

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Disclaimer:- your question is incomplete, please see below for the complete question.

_____ tends to be around zero,suggesting little direct environmental influence on the traits of extraversion and neuroticism.

A)Correlations between identical twins

B)Correlations between fraternal twins

C)Correlations between adoptive parents and their adopted children

D)Correlations between adopted children and their biological parents

flow micro fluorometric analysis of nuclear dna in cells from solid tumors and cell suspensions a new method for rapid isolation and staining of nuclei

Answers

Answer:

D

Explanation:


Propose an artificial diet that would eliminate the need for one of the first three steps in food processing.

Answers

Without the need for mechanical or chemical digestion, a liquid diet comprising glucose, amino acids, and other building blocks might be consumed and absorbed.

Which vitamins and minerals can be consumed without digestion?Foods must be tiny enough for your small intestine's cells to absorb them in order for you to be able to extract nutrients from them. Your food's particle size is decreased during digestion so that absorption may take place. However, some of the macronutrients in your diet, such carbohydrates and amino acids, are already tiny enough to not need to be digested. Other nutrients, such as vitamins and minerals, are present in food as tiny molecules that can be taken in whole.

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_____, a natural constituent of blood, acts as an antithrombin and prevents clots from forming in vessels.

Answers

According to the research, the correct option is Heparin. It is a natural constituent of blood, acts as an antithrombin and prevents clots from forming in vessels.

What is Heparin?

It is a natural anticoagulant or natural mucopolysaccharide, which inhibits the coagulation process, enhancing the effect of antithrombin-III, which is produced by basophils and mast cells found in the lungs and liver.

In this sense, it works by preventing thrombi from appearing in blood vessels, it can also be supplied exogenously as an anticoagulant in this setting, heparin is injected into the blood to prevent clots or thrombi from forming.

Therefore, we can conclude that according to the research, the correct option is Heparin. It is a natural constituent of blood, acts as an antithrombin and prevents clots from forming in vessels.

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deceptive packaging includes exaggerating package contents through subtle design and misleading labels. As of June 28, 2020, Cedar Fair had issued $201.5 million in season passes. Cedar Fair estimated that guests would use passes worth$41.9 million during the remainder of 2020, $61.9 million from January 1 to June 30, 2021, and the remaining $97.7 million after June30, 2021. What amounts should Cedar Fair classify as current versus noncurrent, in its balance sheet on June 28, 2020? PLEASE WHAT IS THE LIMIT HELP IM SOBBING CRYING THANKS i need help ! pls ive been having a hard time with it ive looked at it 100 times which modern sociological theory attempts to understand social behavior by examining the ways people interpret and give meaning to social signals and signs How can diversity enrich the operations and effectiveness of sport organizations? 1 whole note + 2 half notes - 1 quarter note =Please I need help what is the question will mark brainliest. Use the value of the ratio to fill in the following two multiplicative comparison statements. a. The number of pancakes made is ________ times the amount of cups of flour needed. b. The amount of cups of flour needed is ________ of the number of pancakes made Which generalization can be made about the climate of these two areas? san antonio, texas, experiences more dramatic seasonal changes because land heats up and cools down more slowly than water. san antonio, texas, experiences milder seasonal changes because land heats up and cools down more slowly than water. palm coast, florida, experiences more dramatic seasonal changes because water heats up and cools down more slowly than land. palm coast, florida, experiences milder seasonal changes because water heats up and cools down more slowly than land. Quadrilateral ABCD is a rectangle. Find the coordinates for Point B. A client who was injured while playing basketball reports an extremely painful elbow, which is very edematous. What type of injury has the client experienced? as you read this words in your chair, how fast are you moving relative to the chair? relative to the sun? A set of 10 scores has ss = 90. if the scores are a sample, the sample variance is ____, and if the scores are a population, the population variance is ____. Write the first six terms of the arithmetic sequence with the first term, a1, and common difference, d. a1 = 2, d=3 what is the answer of 20 plus 12 a force f1 of magnitude 106.1 lb is directed vertically upward. find a second force f2 that will produce a resultant force of 150.048 lb, 45.0 to the right of f1. Andy and his friend sam were walking along the road together. andy had a big bag of marbles. unfortunately the bottom of the bag split and all the marbles spilled out. poor andy! one third of the marbles rolled down the slope too quickly for andy to pick them up. one sixth of all the marbles disappeared into the rain-water drain. andy and sam picked up all they could but half of the marbles that remained nearby were picked up by other children who ran off with them. andy counted all the marbles he and sam had rescued. he gave one third of these to sam for helping him pick them up. andy put his remaining marbles into his pocket. there were 14 of them. how many marbles were there in andy's bag before the bottom split? Identify and explain two ways Jonah could add value to his toys What were the political changes that occured during the transition form Royal Period to Trustee Period. Answer the question by 1) RESTATE the question AS A STATEMENT. 2) Include an ANSWER to the question. 3) CITE evidence from that supports your answer 4) EXPLIN how the evidence supports your claim (answer) 5) Summarize your ideas in 1-2 sentences.HELP MEEEEEEEEEEEEEEEEEEEEEEEEEEE Who besides Hamilton contributed to the federalist papers?