The application of the colchicines causes microtubules to disintegrate and then when applied to the axon they disrupts the path for the anterograde transport. As a result, all the movement of the material from the soma to the terminal (anterograde transport) ceases. If the colchicine application does not kill the whole of cell, then the material to be transported as will as accumulate on the side of the axon to closest to the soma.
The Colchicine is the medicine for treating the inflammation and pain. It can also be used to: treat the flare-ups (attacks) of gout. to prevent and increased flare-ups of gout when you first start on the medicine like allopurinol – to be taken to manage your condition long term. the Colchicine is in a class of the medications called as anti-gout agents. It works by stopping the natural processes that is cause by swelling and other symptoms of gout and the FMF also.
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When a signal transduction pathway in wolves a phosphorylation cascade, how does the cell's response get turned off?
Protein phosphates reverse the effects of kinases, and unless the signaling molecule is at such a high concentration that it is constantly rebinding the receptor, phosphatases will revert back all kinase molecules to their inactive states.
A phosphorylation cascade is a series of signaling pathway events that occur when one enzyme phosphorylates another, resulting in a chain reaction that phosphorylates thousands of proteins. This can be seen in the signaling of hormone messages.
A signaling pathway starts at the cell surface, where a protein or hormone binds to an Extracellular matrix receptor.
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Sensory input from muscles and organs are sent to ____ whereas sensation one gets from holding a cup of hot coffee is sent to _____.
Sensory input from muscles and organs are sent to cerebellum whereas sensation one gets from holding a cup of hot coffee is sent to somatosensory cortex.
The brain is a complex organ that has various important roles to play in the maintenance of the body. One such role is to identify a stimulus and generate a response.
The cerebellum is the part of the brain that is involved in muscle control, ocular reflexes, motor coordination, maintaining balance etc. Hence, sensory input from muscles and organs will be sent to the cerebellum part of the brain.
As the name suggests, the somatosensory cortex part of the brain is the region that is involved in the maintenance of sensory information. As holding a cup requires touching sensations hence somatosensory cortex part of the brain will be involved in such an action.
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When an action potential reaches a nerve terminal, what type of voltage-gated channels are opened and result in the fusion of synaptic vesicles with the cell membrane?
When an action potential reaches a nerve terminal Ca 2+-channels open and result in the fusion of synaptic vesicles with the cell membrane.
What happens when an action potential reaches the nerve terminal ?Neurons communicate with one another via synapses. When an action potential reaches the presynaptic terminal, neurotransmitter is released from the neuron into the synaptic cleft, which is a gap of 20-40nm between the presynaptic axon terminal and the postsynaptic dendrite (often a spine).
Why do voltage-gated potassium channels open?K+ efflux is supported by voltage-gated potassium channels (KV), which open in response to membrane depolarization.
What happens to voltage-gated sodium channels at threshold?Depolarization opens more voltage-gated sodium channels at the threshold. This allows additional sodium to enter the cell, causing it to depolarize further and open even more voltage-gated sodium channels. This positive feedback loop causes the action potential to rise.
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The scientist whose work provided the foundation for later understandings of genetics was?
Answer:
Charles Darwin.
Explanation:
I need info about heck cattle
Answer:
Heck cattle originated in Germany in the 1920s and 1930s in an attempt to breed back domestic cattle to their ancestral form: the aurochs (Bos primigenius primigenius).[2] In the first years of the Weimar Republic, the brothers Heinz and Lutz Heck independently started their extensive breeding-back programmes.[3]
Their motivation was to rescue the aurochs from oblivion because it was constantly confused with the European bison, the other large bovine of Holocene Europe. The Heck brothers believed that creating a look-alike and showing both species next to each other would help to show the difference between the two species to a broader public. Apart from that, they believed they were able to reconstruct the species and therefore to correct the mistake man made when killing the species off.[4]
Heinz was the director of the Hellabrunn Zoological Gardens in Munich and Lutz of the Berlin Zoological Gardens. Only eleven years after they started their breeding experiments, just as the Weimar Republic was drawing to a close, they each announced success.[5][6]
Lutz Heck used Spanish Fighting Bulls for his breed, some of which were released in the Polish Romincka Forest, but survived until the late 1940s when they were killed during the end of the Second World War.[7] Rewilding Lutz Heck's cattle breed was met with objection since the beginnings of this project, as these cattle were aggressive and their ecological impact on the native fauna was considered to be unpredictable. Later rewilding attempts in Poland were rejected.[8]
Lutz Heck's cattle were exterminated at the end of the Second World war. Heinz Heck used a different set of breeds, all of the living Heck cattle go back to his stock.[1] The ancestral breeds used by Heinz Heck include:
Hungarian Grey Cattle
Highland Cattle
Corsican Cattle
Murnau-Werdenfels Cattle
Angeln cattle
Black-pied lowland cattle
White Park Cattle
Brown Swiss
In 1932 the first bull that Heinz Heck believed to resemble the aurochs was born and named Glachl. He was a 75% Corsican and 25% (Gray cattle × Lowland × Highland × Angeln) cross. This bull and his father were subsequently bred into further breeds to increase weight.[1] As a consequence most modern Heck cattle go back to Central European dairy and beef cattle that were supplemented by cattle from other regions.[9] Advocates of Heck cattle often claim that Heinz′ and Lutz′ breeding results looked largely identically, thus ″proving the success″ of their experiment. However Berlin and Munich Heck cattle did not look very similar.[1]
Distribution
There are about 2000 Heck cattle in Europe and few elsewhere. Heck cattle are found in German zoos because of the erroneous claim by the Heck brothers that these cattle represent resurrected aurochs and are suitable for conservation projects today. In Oostvaardersplassen in Flevoland (Netherlands), about 600 Heck cattle roam freely. Weak animals are shot by hunters in order to prevent unnecessary suffering.[10] Others are at the Falkenthaler Rieselfelder near Berlin, at the Nesseaue nature reserve near Jena, Thuringia and at the Grubenfelder Leonie nature reserve in Auerbach, Bavaria. About 100 were registered in France in 2000. The introduction of Heck cattle into nature reserves in order to restore ancient landscapes inspired Rewilding Europe.[11] The way of no interference in the Oostvaardersplassen, however, was terminated in 2018, as large numbers of cattle died of starvation during the cold winters of 2005 and 2010, which caused a loss of public support.[12]
Criticism
Gargle with warm and salt water kills the tonsils germs and prevent from them from leaking into lungs do you believe in the pieces of information?
Answer:
Yes I believe this information to be true.
Explanation:
It is believed that saline (salt water) can help you get over a cold faster.
Differentiation requires __________ of particular genes to produce cell populations with __________ capabilities that form tissues.
Differentiation requires inactivation of particular genes to produce cell populations with limited capabilities that form tissues.
Differentiation is the process by which the stem cells that are dividing to form new cells become specialized to perform a particular function assigned to them.
It is important to produce the different variety of cells that are required for the functioning of the body.
Inactivation is a condition in which certain genes are shut down during embryo development so that the cells differentiates into a particular type of cell. It enables the developing cell to get accommodated with functioning of only certain types of proteins.
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Unrelated males are most likely to be found in what sort of coalition? in other words, unrelated males have the best chance of a fitness benefit in which type of coalition?
Unrelated males are most likely to be found in a kinship sort of coalition.
Kinship coalition does not describe aptitude benefit because it suggests that this man has both parents and has received their traits from them. It is the connection between adopter and adopted, as well as between persons who are descended from the same trunk or from other trunks.
With this knowledge, we can draw the conclusion that Men without kin are unlikely to be discovered because, according to the definition of kinship, a man is considered to be kin if he has a father and a mother and has inherited their traits; therefore, kinship does not necessarily define an advantage in terms of aptitude.
Male reproductive coalitions are best understood as a particular instance of cooperative competition within the context of traditional male-male conflict.
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estimating the probability of illness due to swimming in recreational water with a mixture of human- and gull-associated microbial source tracking markers
Numerous sources of feces frequently pollute beaches. Raw and processed wastewater from humans and wildlife, such seagulls, are examples of animal sources.
Different sources of pollution are expected to pose different health risks to swimmers. Genetic Microbial Source Tracking (MST) markers can be used to detect bacteria associated with various animal sources, but the health risks associated with admixture of MST markers are unknown. In this study, we show how to predict these health risks using markers associated with humans and seagulls as examples. A quantitative microbial risk assessment (QMRA) is performed using MST markers as indicators. We find that the risks associated with exposure to specific concentrations of human-associated MST (HF) markers are greater when the HF sources are raw and untreated wastewater. We also found a risk-based threshold for HF from untreated beach wastewater to fall below his predicted disease risk of 3 per 100 swimmers, a function of seagull-associated MST marker (CAT) concentration. It also provides values.
However, using a combination of human- and gull-associated microbial source tracking markers to calculate the likelihood of sickness brought on by swimming in recreational water.
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Nucleotides are the building blocks for
a.fats
b.proteins
c. nucleic acids
d.carbohydrates
Donald macleod of princeton theological seminary tells his seminarians that the maximum time for an effective sermon is?
Donald Macleod of Princeton theological seminary tells his seminarians that the maximum time for an effective sermon is 18 minutes.
Theology is the systematic observe of the character of the divine and, more substantially, of non secular belief. it is taught as an academic situation, generally in universities and seminaries. An instance of theology is the have a look at of God. An organized approach of interpreting non secular works and beliefs into practical shape. The have a look at of God, or a god, or gods, and the truthfulness of religion in widely known.
Theological research is lots more than the examine of a holy text similar to the Bible or the Quran. it's far the systematic have a examine of traditions, observation, and ideas of a specific religion's divine and religious truths. areas of focus may also moreover encompass.
Theology offers the opportunity to attention on the Christian faith in element, through the check of the Bible, the records of Christianity, its key thinkers and its influence on ethical debates and the moves of its believers.
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If the amount of urine produced were different in the two conditions, how would that affect your calculation? Explain.
Yes, the ratio's value will alter if the amounts of urine production are not equal. If the blood osmolarity is higher than the urine osmolality, then the blood contains more solutes than the urine does, and vice versa.
What is Osmotic homeostasis?Weather and temperature have an impact on osmotic homeostasis. When osmoregulation occurs, the amount of salt and water in the blood is kept at a constant level.
Osmoregulation is essential for preserving the concentrations balance (both inside and outside of the cell).
How would it change your computation if the amount of pee generated under the two circumstances varied?Because the blood contains an excessive amount of water or fluid, increased urine production can lower the osmolality of urine. Urine osmolality will rise as the body becomes dehydrated or has less fluid intake.
Antidiuretic hormone will be produced by the body in response to higher urine osmolality. The presence of Addison disease and other disorders may be indicated by urine osmolality readings that are higher than the normal value.
Therefore, it also influences the computations if the environment and urine production are different.
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what structure in the heart transfers the electrical signal from the sinoatrial (sa) node to the atrioventricular (av) node?
The internodal pathways are responsible for the transfer of electrical signals from the sinoatrial node to the atrioventricular node.
There are three internodal pathways according to the anatomical evidence; anterior Bachman's bundle, middle Wenkebach's bundle, and posterior Thorell's bundle. Due to this the impulse is delayed for a very short period. The upper heart chambers contract as a result of an electrical signal produced by the (SA) sinoatrial node. The signal is subsequently transmitted by the AV (atrioventricular) node, which causes the lower heart chambers i.e. the ventricles to contract or pump. The heart's pacemaker is regarded to be the SA node.
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Why does acute renal failure occur in patients with acute lymphoblastic leukemia?
Learning is defined as a change in behavior as a result of experience. In a short essay (100-150 words), describe the role of heritable information in the acquisition of learning, using some examples from imprinting and associative learning.
Learning is the process by which an organism's experience results in a behavioral adaptation.
Behavior of the organism is the environmental component that causes specific alteration.The structure of the nervous system makes learning possible, and each creature has a unique capacity for learning. Imprinting is a sort of learning that fosters species identification. For instance, after hatching, ducks or geese start the process of imprinting. They observe their mother to learn how to swim and get food. It can be learned or it might be innate.A sensitive period is the time when an organism is being imprinted by its adults. But some habits are ingrained; children inherit them from their parents.The kind of learning that comes through experience is known as associative learning. It is not passed on from parents. Associative learning includes, for instance, learning to ride a bike. Bicycle riding skills are not handed down to the next generation.Similar to this, if someone develops an allergy to a certain food, they may come to identify that food with allergies and stop eating it.Every person engages in associative learning on a regular basis when they interact with their environment. The ability to learn, however, may vary amongst species.Learn more about the Associative learning with the help of the given link:
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Identify the variables in this hypothesis. if an object's mass is increased, then the object's acceleration will decrease, because the object will be more resistant to change in motion. the independent variable is . the dependent variable is .
a) The independent variable is mass.
b) The dependent variable is acceleration.
Variables in research are any characteristics that can have several values. To examine cause-and-effect correlations, researchers often modify or measure independent and dependent variables in experiments.
The variable that can be manipulated or changed in an experimental study to examine its effects is known as an independent variable. It is unaffected by any other variables in the study. Hence, mass is an independent variable because it is unaffected by acceleration.
Similarly, the variable that changes as a result of the modification of the independent variable is known as a dependent variable. It is the outcome that is being measured, and its value "depends" on the independent variable. Hence, acceleration is a dependent variable because its value depends on the mass.
Therefore, in the stated hypothesis, mass is the independent variable and acceleration is the dependent variable.
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Identify the variables in this hypothesis
If an object's mass is increased, then the object's acceleration will decrease, because the object will be more resistant to change in motion.
a) The independent variable is _____
- mass
- acceleration
- motion
b) The dependent variable is _____
- mass
- acceleration
- motion
The data in Jost's experiment could be explained if some aspect of the surgery other than gonad removal caused female genitalia to develop. If you were to repeat Jost's experiment, how might you test the validity of such an explanation?
If some aspect of the surgery other than gonad removal caused female genitalia to develop, then to test the validity of such an explanation we could perform a sham surgery on embryos.
The information got from Jost's experiment could likewise be made sense of by carrying out a sham surgery on the embryonic gonad cells. This speculation can be tried by basically analyzing and opening the embryo without eliminating the gonadal tissues.
Genitalia: The organs which comprise the reproductive arrangement of the mammalian body are altogether indicated with the term genitalia. It contains the outer and inside reproductive organs and is different in the account of females and males.
Among these designs, the gamete-producing organs of the reproductive framework are signified as gametes.
By an elective clarification, female genitalia may likewise create without eliminating the gonads on the off chance that the undeveloped gonadal cells are exposed to sham surgery (a careful technique wherein a few remedial advances are skipped).
The speculation of farce a sham surgery can be approved by testing a few embryos in which, rather than eliminating the gonadal cells, these are recently taken apart and left open.
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A white rabbit with dark ears sitting in the snow. during the winter, this species of hare has white fur, but in the summer, it has brown fur. what environmental change may have led to this hare's fur color? drought snow cover asteroid impact global warming
Answer:
The environmental change that may have led to this hare's fur coloration is snow cover.
Answer:
b
Explanation:
edge 2023
ding information regarding the endocannabinoid system (ecs) and endocannabinoid deficiency syndrome.
ECS has helped in the discovery of many cannabinergic, canned, cannabimimetic drugs.
ECS is the Endocannabinoid System whose main function is to maintain homeostasis i.e. condition of a balanced internal condition. Along with this it also maintains physiological activities such as pain, emotional behavior, pain, anxiety, pregnancy, learning, and memory. It also takes part in cancer and other neurodegenerative disease cases.
The help of ECS genetic manipulation has led to the discovery of many drugs and medicines. Many cannabinergic, canned, cannabimimetic drugs have developed that either inhibit metabolic pathways or antagonize the ECSs receptors and modulate ECS.
All these activities may prove to be beneficial in treating several diseases.
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An action potential is an all-or-none event. This on/off signaling is an evolutionary adaptation of animals that must sense and act in a complex environment. It is possible to imagine a nervous system in which the action potentials are graded, with the amplitude depending on the size of the stimulus. What evolutionary advantage might on/off signaling have over a graded (continuously variable) kind of signaling?
The action potential is produced and the nerve impulse propagates to the following neuron if the membrane potential surpasses the threshold level.
What is evolutionary advantage might on/off signaling?Action potential or nerve impulse generation is an all or nothing reaction in this. The interior of the nerve cell is negatively charged.
The cell is polarized, and there are significant amounts of due positive ions present when the cell is at rest.
If the stimulus falls short of the threshold, the membrane potential levels off, and no impulse is produced.
If the stimulus falls short of the threshold, the membrane potential levels off, and no impulse is produced.
Therefore, evolutionary advantage might on/off signaling have over a graded (continuously variable) kind of signaling.
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How is it possible for all three states of water to coexist on earth at the same time?
Answer:
Different temperatures.
Explanation:
AT room temperature water is liquid, at 32 degrees f it freezes, and at 212 degrees f, it boils, or becomes a gas.
Since these tempretures all exist on earth, water exists in all of these forms
What mechanisms have evolved in animals with
b. internal fertilization that help ensure that offspring survive to adulthood?
Complete Question-
What mechanisms have evolved in animals with
(a) external fertilization and
(b) internal fertilization that help ensure that offspring survive to adulthood?
Mechanisms have evolved in animals with is In internal fertilization, the eggs are either grown in a secure reproductive canal or are protected when laid by a shell, a defense mechanism exhibited by animals like mammals, reptiles, and birds.
When gametes combine inside the female body, this process is known as internal fertilization. The female reproductive system receives the male gamete, which then swims to the egg to fertilize it.
Either the mother feeds the eggs or they are placed with a hard covering to protect them from environmental risks. These systems aid species like birds, reptiles, and mammals in boosting the survival of their progeny.
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The surface indentation that separates the atria from the ventricles is known as the?
Atrioventricular septum is the surface indentation that separates the atria from the ventricles.
What is an atrioventricular septum?The interatrial and interventricular septal cross the atrioventricular annular plane and merge with the septum tricuspid and anterior mitral leaflet attachment at the septal atrioventricular junction, which is a critical region of the heart.
The tricuspid and mitral valves seem cruciate on a four-chamber view when both septa are converging, earning the term crux of the heart, cardiac crux, or crux cordis.
The atrioventricular septum, a septal component dividing the atria from the left ventricle, is a distinctive anatomic characteristic of the atrioventricular junction.
Therefore, the atrioventricular septum is the indentation that separates the atria from the ventricles.
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The process by which continuous exposure to a stimulus affects the comprehension of and response to the stimulus is known as _____.
The process by which continuous exposure to a stimulus affects the comprehension of and response to the stimulus is known as habituation.
What is a stimulus?A stimulus is a factor, substance or event which produces a response in an organ or tissue or even cell of living organisms.
Stimulus are received by specialized receptors present in cells which then send the stimulus to he brain for processing resulting in a response to the stimulus.
Continuous exposure to a stimulus will affects the comprehension of and response to the stimulus. This phenomenon is known as habituation.
In conclusion, the response of the body to stimulus can be affected by the frequency of exposure to the stimulus.
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inmicroglial inflammatory signaling orchestrates the hypothalamic immune response to dietary excess and mediates obesity susceptibility.valdearcos m, douglass jd, robblee mm, dorfman md, stifler dr, bennett ml, gerritse i, fasnacht r, barres ba, thaler jp, koliwad sk.cell metab. 2018 jun 5;27(6):1356. doi: 10.1016/j.cm
A hypothalamic immune response is directed by microbial inflammatory signaling stimulated by dietary excess.
Pro-inflammatory microglia accumulation in Mediobasal hypothalamus is due to excess diet. But its side effects are uncertain. A study was conducted on mice to know if the immunological response of MBH is determined by microbial inflammatory signaling. Microgliosis was decreased by either selectively depressing microglia NF -κB-dependent or pharmacologically decreasing microglia.
An effect was observed that restricted the weight gain and hyperphagia and entry of MBH by myeloid cells. But when negative NF-κB regulator A20 was induced to activate microbial, effects such as weight gain, less energy expenditure, and cellular infiltration were observed even in the absence of excess diet.
Therefore, a hypothalamic immune response is directed by microbial inflammatory signaling stimulated by dietary excess.
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Neurons that respond to specific qualities of objects, such as orientation, movement, and length, are called.
Neurons that respond to specific qualities of objects, such as orientation, movement, and length, are called feature detectors.
What are feature detectors?Detection of the characteristics of objects is important for the brain to know how to classify stimuli and can obtain signals that may be important by eliminating signals that do not contribute anything. The feature detectors are a group of neurons found in the brain which carry out this activity, filtering out important stimuli. It does this by inputting information through the sensory pathway.
Therefore, we can confirm that neurons that respond to specific qualities of objects, such as orientation, movement, and length, are called feature detectors.
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What is the name given to the smallest group of atoms, ions, or molecules that form the building block of a mineral?.
Morgan's mitochondrial myopathy is due to a genetic defect. Which of the
following statements provides evidence that this is a hereditary disorder?
O A. Morgan is not capable of synthesizing glucose in her
mitochondria due to the absence of cristae.
OB. Morgan does not produce enough ATP due to infection by a
parasite.
C. Morgan's cells do not produce a protein needed for optimal
mitochondrial function.
D. Morgan's condition is temporary, and her mitochondria will
eventually return to normal function.
The statement Morgan's cells do not produce a protein needed for optimal mitochondrial function provides evidence that this is a hereditary disorder (Option c).
What is a hereditary disorder?A hereditary disorder is a type of disease transmitted across generations based on defective genetic information, which leads to faulty protein synthesis.
In conclusion, the statement Morgan's cells do not produce a protein needed for optimal mitochondrial function provides evidence that this is a hereditary disorder (Option c).
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In some animals, females select males as mates based on their ability to ward off infection as indicated by traits that the males possess. This is an example of ________.
In some animals, females select males as mates based on their ability to ward off infection as indicated by traits that the males possess. This is an example of honest signaling.
When females select males as mates based on their ability to ward off infection as indicated by traits that the male possess is considered signaling. Signaling theory is a corpus of theoretical work that studies communication between individuals, both within and between species, in evolutionary biology.
The key question is whether creatures with competing interests, such as those involved in sexual selection, can be expected to give honest signals instead of deceiving. Mathematical models explain how signaling might support an evolutionary approach that is stable.
Signals are delivered in situations like mate choice by females, which puts selective pressure on the signals of the advertising males. Signals change the behavior of the receiver in favor of the signaller, which causes them to develop. Signals can be honest, providing information that helps the recipient become more fit, or they might be dishonest. A person can lie by sending a deceptive signal.
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The nucleophile of the first step of spliceosome-mediated pre-mrna splicing is the?
The nucleophile of the first step of the spliceosome-mediated pre-mRNA splicing is the: A. 2' hydroxyl of the branch to point adenosine.
The spliceosome is the large RNA-protein that complex that catalyses the removal of the introns from the nuclear pre-mRNA. A wide range of the biochemical and the genetical studies shows that the spliceosome was comprises three major form of RNA-protein subunits, the U1, U2 and [U4/U6. Most of the splicing occurs in between the exons on the single the RNA transcript, but they occasionally trans-splicing occurs, in which the exons on the different pre-mRNAs are they ligated together. The splicing is process that occurs in the cellular machines called as spliceosomes, in which the snRNPs are to be found along with additional proteins.
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